Watch Intently (one)oxcarbazepine will lessen the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of fentanyl with CYP3A4 inducers could lead on to a lessen in fentanyl plasma concentrations, not enough efficacy or, possibly, advancement of the withdrawal syndrome… Read More

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